Blastomycosis (Gilchrist's disease) is a group of chronic non-contagious diseases related to deep mycoses, affecting the skin, bones, mucous membranes and internal organs. The disease was called Gilchrist disease, named after the American dermatologist Thomas Casper Gilchrist (1862-1927), who has first described it.
Etiology of blastomycosis. The disease causes yeast and yeast-like fungi. The reservoir of pathogens of blastomycosis is the soil. Infection usually occurs by inhaling fungus spores with dust. Mostly sick people working in agriculture.
Pathological anatomy of blastomycosis. The disease begins with the appearance of small round red papules mainly on the exposed parts of the skin: face, hands, forearms, etc. Part of the papules soon turns into pustules, opening with the release of purulent bloody fluid and the subsequent formation of crusts. As a result of the fusion of these elements, more or less large infiltrated, less painful ulcers are formed, in the center of which papillary and warty growths are formed, covered with serous-purulent discharge. The skin around the hearth is often dark purple; In this zone, you can see miliary pustules.
Lesion of the larynx in an isolated form is extremely rare, often it occurs in conjunction with blastomatosis of the lungs or skin. When laryngoscopy at the beginning of the disease, a dark red swelling in the epiglottis, aryepiglottic folds and other areas of the mucosa is determined. Soon on this swelling appears small yellowish nodules, transforming into pustules containing a purulent-bloody fluid. These pustules are scarred, and in their place, in the chronic course of the disease, there are new ones.
Symptoms and clinical course. When the larynx is ill, patients usually present the same complaints as with sporotrichosis, but these complaints are rarely taken into account due to the general severe condition, especially with concurrent blastomatosis of the lungs.
The diagnosis of the disease is the same as with sporotrichosis of the larynx.
Treatment is practically the same as for sporotrichosis.